While my parents were here, we went up to Charleston one day. It was a bit cold, but we enjoyed lunch and some shopping in the historic district. We then took the kids to the South Carolina Aquarium. They had a BALL!! We had a lot of fun too.
Another trip we took was to the beach at St. Helena Island. That day it was quite warm (upper 70's -- eat your heart out Pacific Northwesterners!!) and so the kids played in the sand and waves while the adults soaked up some warmth.